A comparative study between the use of the combination of trichloroacetic acid peeling with hydroquinone and hydroquinone alone in patients with melasma

Background: Melasma is a common acquired pigmentary disorder that aesthetically displeasing. Kligman’s and Modified formula using topical steroids, hydroquinone retinoids, various other depigmenting agents being widely used all over for melasma with varying results. Chemical peeling newly added to the therapeutic armamentarium showing encouraging results worldwide in patients melasma. However, comparative studies are lacking abundance our part of world. Aims Objectives: To determine if serial trichloroacetic acid peels provide additional benefits when combined time-tested therapy 4% Materials Methods: Fifty were divided into two groups 25 each. One group received peel 4%. The only cream. evaluated by clinical investigator both subjectively photographs taken at baseline, 12 weeks, 21 weeks. For evaluation, area severity index (MASI) was used. Results: A significant decrease MASI score from baseline weeks observed (P<0.001). receiving 20% showed trend toward more rapid greater improvement, statistically Only few side effects group. Conclusion: This study demonstrates an effect regimen cream treating Fitzpatrick skin types III above judiciously under supervision. It superficial chemical can be as adjunct better efficacy treat